Metabolomics: a global biochemical approach to the study of central nervous system diseases.

Journal Article (Journal Article;Review)

Metabolomics, the omics science of biochemistry, is a global approach to understanding regulation of metabolic pathways and metabolic networks of a biological system. Metabolomics complements data derived from genomics, transcriptomics, and proteomics to assist in providing a systems approach to the study of human health and disease. In this review we focus on applications of metabolomics for the study of diseases of the nervous system. We share concepts in metabolomics, tools used in metabolic profiling and early findings from the study of neuropsychiatric diseases, and drugs used to treat these diseases. Metabolomics emerges as another powerful tool in central nervous system research.

Full Text

Duke Authors

Cited Authors

  • Kaddurah-Daouk, R; Krishnan, KRR

Published Date

  • January 2009

Published In

Volume / Issue

  • 34 / 1

Start / End Page

  • 173 - 186

PubMed ID

  • 18843269

Electronic International Standard Serial Number (EISSN)

  • 1740-634X

Digital Object Identifier (DOI)

  • 10.1038/npp.2008.174


  • eng

Conference Location

  • England