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Establishing reporting standards for metabolomic and metabonomic studies: a call for participation.

Publication ,  Journal Article
Fiehn, O; Kristal, B; van Ommen, B; Sumner, LW; Sansone, S-A; Taylor, C; Hardy, N; Kaddurah-Daouk, R
Published in: OMICS
2006

Metabolite concentrations in cellular systems are very much dependent on the physiological, environmental, and genetic status of an organism and are regarded as the ultimate result of cellular regulation, resulting in the visible phenotypes. Therefore, the comprehensive analysis of metabolite levels and fluxes renders a suitable tool for assessing the degree of perturbation in biological systems. Lessons derived from development of other OMICS areas (genomics, proteomics, and transcriptomics) have shown that large-scale comparisons and interpretations will require the re-use of data over long periods of time and by multiple laboratories with different expertise and backgrounds. Reaching this goal will require standardization of reporting structures of metabolomic studies for journal publication purposes, for regulatory deposition, and for database dissemination. An initiative by the Metabolomics Society is presented that aims to define important aspects of metabolomic workflows. These include biological study designs, chemical analysis, and data processing, as well as the ontologies that are necessary in this framework.

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Published In

OMICS

DOI

ISSN

1536-2310

Publication Date

2006

Volume

10

Issue

2

Start / End Page

158 / 163

Location

United States

Related Subject Headings

  • Vocabulary, Controlled
  • Societies, Medical
  • Research Design
  • Metabolism
  • Humans
  • Databases, Factual
  • Bioinformatics
  • Animals
  • 31 Biological sciences
  • 06 Biological Sciences
 

Citation

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Chicago
ICMJE
MLA
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Fiehn, O., Kristal, B., van Ommen, B., Sumner, L. W., Sansone, S.-A., Taylor, C., … Kaddurah-Daouk, R. (2006). Establishing reporting standards for metabolomic and metabonomic studies: a call for participation. OMICS, 10(2), 158–163. https://doi.org/10.1089/omi.2006.10.158
Fiehn, Oliver, Bruce Kristal, Ben van Ommen, Lloyd W. Sumner, Susanna-Assunta Sansone, Chris Taylor, Nigel Hardy, and Rima Kaddurah-Daouk. “Establishing reporting standards for metabolomic and metabonomic studies: a call for participation.OMICS 10, no. 2 (2006): 158–63. https://doi.org/10.1089/omi.2006.10.158.
Fiehn O, Kristal B, van Ommen B, Sumner LW, Sansone S-A, Taylor C, et al. Establishing reporting standards for metabolomic and metabonomic studies: a call for participation. OMICS. 2006;10(2):158–63.
Fiehn, Oliver, et al. “Establishing reporting standards for metabolomic and metabonomic studies: a call for participation.OMICS, vol. 10, no. 2, 2006, pp. 158–63. Pubmed, doi:10.1089/omi.2006.10.158.
Fiehn O, Kristal B, van Ommen B, Sumner LW, Sansone S-A, Taylor C, Hardy N, Kaddurah-Daouk R. Establishing reporting standards for metabolomic and metabonomic studies: a call for participation. OMICS. 2006;10(2):158–163.
Journal cover image

Published In

OMICS

DOI

ISSN

1536-2310

Publication Date

2006

Volume

10

Issue

2

Start / End Page

158 / 163

Location

United States

Related Subject Headings

  • Vocabulary, Controlled
  • Societies, Medical
  • Research Design
  • Metabolism
  • Humans
  • Databases, Factual
  • Bioinformatics
  • Animals
  • 31 Biological sciences
  • 06 Biological Sciences