Neonatal Job's syndrome featuring a vesicular eruption.

Journal Article (Journal Article)

A newborn infant who developed a vesicular eruption, clinically indistinguishable from herpetic lesions, eventually developed the classic features of Job's syndrome. The initial ares of involvement included the hands and feet, then the scalp, face, and suprapubic skin. The clear, tense vesicles varied only slightly in size and appeared as isolated, grouped, or confluent lesions on inflamed skin. Many eventually became umbilicated. The more typical eczematous component appeared over the course of the next several months. Although the child initially had an elevated white blood cell count and eosinophilia, his IgE level did not become dramatically elevated until after 1 year of age. Job's syndrome should be considered as part of the differential diagnosis of a vesicular eruption in the newborn.

Full Text

Duke Authors

Cited Authors

  • Kamei, R; Honig, PJ

Published Date

  • May 1988

Published In

Volume / Issue

  • 5 / 2

Start / End Page

  • 75 - 82

PubMed ID

  • 3412996

International Standard Serial Number (ISSN)

  • 0736-8046

Digital Object Identifier (DOI)

  • 10.1111/j.1525-1470.1988.tb01142.x


  • eng

Conference Location

  • United States