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Parc-ing p53 in the cytoplasm.

Publication ,  Journal Article
Kastan, MB; Zambetti, GP
Published in: Cell
January 10, 2003

Nikolaev et al. (this issue of Cell) report the identification of a parkin-like protein, Parc, and its role in anchoring the tumor suppressor protein p53 in the cytoplasm reveals yet another level of control of p53 function. Regulation of the subcellular localization of p53 by Parc may serve as a novel target in treatment of certain types of tumors.

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Published In

Cell

DOI

ISSN

0092-8674

Publication Date

January 10, 2003

Volume

112

Issue

1

Start / End Page

1 / 2

Location

United States

Related Subject Headings

  • Ubiquitins
  • Ubiquitin-Protein Ligases
  • Tumor Suppressor Protein p53
  • Tumor Cells, Cultured
  • Proto-Oncogene Proteins c-mdm2
  • Proto-Oncogene Proteins
  • Protein Structure, Tertiary
  • Nuclear Proteins
  • Neuroblastoma
  • Neoplasm Proteins
 

Citation

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Kastan, M. B., & Zambetti, G. P. (2003). Parc-ing p53 in the cytoplasm. Cell, 112(1), 1–2. https://doi.org/10.1016/s0092-8674(02)01281-3
Kastan, Michael B., and Gerard P. Zambetti. “Parc-ing p53 in the cytoplasm.Cell 112, no. 1 (January 10, 2003): 1–2. https://doi.org/10.1016/s0092-8674(02)01281-3.
Kastan MB, Zambetti GP. Parc-ing p53 in the cytoplasm. Cell. 2003 Jan 10;112(1):1–2.
Kastan, Michael B., and Gerard P. Zambetti. “Parc-ing p53 in the cytoplasm.Cell, vol. 112, no. 1, Jan. 2003, pp. 1–2. Pubmed, doi:10.1016/s0092-8674(02)01281-3.
Kastan MB, Zambetti GP. Parc-ing p53 in the cytoplasm. Cell. 2003 Jan 10;112(1):1–2.
Journal cover image

Published In

Cell

DOI

ISSN

0092-8674

Publication Date

January 10, 2003

Volume

112

Issue

1

Start / End Page

1 / 2

Location

United States

Related Subject Headings

  • Ubiquitins
  • Ubiquitin-Protein Ligases
  • Tumor Suppressor Protein p53
  • Tumor Cells, Cultured
  • Proto-Oncogene Proteins c-mdm2
  • Proto-Oncogene Proteins
  • Protein Structure, Tertiary
  • Nuclear Proteins
  • Neuroblastoma
  • Neoplasm Proteins