The many substrates and functions of ATM.

Journal Article (Journal Article;Review)

As its name suggests, the ATM--'ataxia-telangiectasia, mutated'--gene is responsible for the rare disorder ataxia-telangiectasia. Patients show various abnormalities, mainly in their responses to DNA damage, but also in other cellular processes. Although it is hard to understand how a single gene product is involved in so many physiological processes, a clear picture is starting to emerge.

Full Text

Duke Authors

Cited Authors

  • Kastan, MB; Lim, DS

Published Date

  • December 2000

Published In

Volume / Issue

  • 1 / 3

Start / End Page

  • 179 - 186

PubMed ID

  • 11252893

International Standard Serial Number (ISSN)

  • 1471-0072

Digital Object Identifier (DOI)

  • 10.1038/35043058


  • eng

Conference Location

  • England