Cilia in vertebrate development and disease.


Journal Article (Review)

Through the combined study of model organisms, cell biology, cell signaling and medical genetics we have significantly increased our understanding of the structure and functions of the vertebrate cilium. This ancient organelle has now emerged as a crucial component of certain signaling and sensory perception pathways in both developmental and homeostatic contexts. Here, we provide a snapshot of the structure, function and distribution of the vertebrate cilium and of the pathologies that are associated with its dysfunction.

Full Text

Cited Authors

  • Oh, EC; Katsanis, N

Published Date

  • February 2012

Published In

Volume / Issue

  • 139 / 3

Start / End Page

  • 443 - 448

PubMed ID

  • 22223675

Pubmed Central ID

  • 22223675

Electronic International Standard Serial Number (EISSN)

  • 1477-9129

Digital Object Identifier (DOI)

  • 10.1242/dev.050054


  • eng

Conference Location

  • England