Cilia in vertebrate development and disease

Journal Article

Through the combined study of model organisms, cell biology, cell signaling and medical genetics we have significantly increased our understanding of the structure and functions of the vertebrate cilium. This ancient organelle has now emerged as a crucial component of certain signaling and sensory perception pathways in both developmental and homeostatic contexts. Here, we provide a snapshot of the structure, function and distribution of the vertebrate cilium and of the pathologies that are associated with its dysfunction. © 2012. Published by The Company of Biologists Ltd.

Full Text

Duke Authors

Cited Authors

  • Oh, EC; Katsanis, N

Published Date

  • 2012

Published In

Volume / Issue

  • 139 / 3

Start / End Page

  • 443 - 448

PubMed ID

  • 22223675

International Standard Serial Number (ISSN)

  • 0950-1991

Digital Object Identifier (DOI)

  • 10.1242/dev.050054