Methods for assessing rat sperm motility.

Published

Journal Article (Review)

Computer-assisted sperm analysis (CASA) systems are becoming more widely used. With this spread of technology come more data from toxicology studies, designed to determine if treatment with putative toxicants affects sperm motion parameters. While these CASA methods provide us with more ways to evaluate toxicity and thus perhaps increase our chances of successfully protecting human health, there is also a greater likelihood that different laboratories will use different methods of collecting data on sperm motility. Different systems used with different methods in different laboratories will inevitably generate data that are difficult to compare. In a prospective attempt to address this issue of comparability and limit the problems, a group of individuals using CASA systems to analyze rat sperm motility convened to discuss methodologic issues, share data, and try to reach a consensus about methods for performing these studies. This article shares those meetings and data in the hope that common methods will enhance interlaboratory comparisons.

Full Text

Duke Authors

Cited Authors

  • Chapin, RE; Filler, RS; Gulati, D; Heindel, JJ; Katz, DF; Mebus, CA; Obasaju, F; Perreault, SD; Russell, SR; Schrader, S

Published Date

  • January 1, 1992

Published In

Volume / Issue

  • 6 / 3

Start / End Page

  • 267 - 273

PubMed ID

  • 1591485

Pubmed Central ID

  • 1591485

Electronic International Standard Serial Number (EISSN)

  • 1873-1708

International Standard Serial Number (ISSN)

  • 0890-6238

Digital Object Identifier (DOI)

  • 10.1016/0890-6238(92)90183-t

Language

  • eng