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The course of cognitive functioning over six months in individuals at clinical high risk for psychosis.

Publication ,  Journal Article
Barbato, M; Colijn, MA; Keefe, RSE; Perkins, DO; Woods, SW; Hawkins, KA; Christensen, BK; Addington, J
Published in: Psychiatry Res
April 30, 2013

Cognitive impairment is common in psychosis and has recently been observed in individuals at clinical high risk (CHR) of developing psychosis. The purpose of this study was to characterize longitudinal change in cognition among CHR individuals, and compare cognition of CHR individuals who later convert to psychosis to that of CHR who do not convert. Participants were tested at baseline and followed-up after six months using a comprehensive cognitive test battery. Individuals who did not convert to psychosis either remained stable or significantly improved in their cognitive performance. At baseline participants who converted to psychosis compared to non-converters exhibited poorer performance in several cognitive tests, suggesting that some cognitive impairment is already present before conversion. Future longitudinal research should address if further decline takes place during the prodrome or after conversion to psychosis.

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Published In

Psychiatry Res

DOI

EISSN

1872-7123

Publication Date

April 30, 2013

Volume

206

Issue

2-3

Start / End Page

195 / 199

Location

Ireland

Related Subject Headings

  • Young Adult
  • Risk
  • Psychotic Disorders
  • Psychiatry
  • Prospective Studies
  • Prodromal Symptoms
  • Neuropsychological Tests
  • Male
  • Longitudinal Studies
  • Humans
 

Citation

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Barbato, M., Colijn, M. A., Keefe, R. S. E., Perkins, D. O., Woods, S. W., Hawkins, K. A., … Addington, J. (2013). The course of cognitive functioning over six months in individuals at clinical high risk for psychosis. Psychiatry Res, 206(2–3), 195–199. https://doi.org/10.1016/j.psychres.2012.10.013
Barbato, Mariapaola, Mark A. Colijn, Richard S. E. Keefe, Diana O. Perkins, Scott W. Woods, Keith A. Hawkins, Bruce K. Christensen, and Jean Addington. “The course of cognitive functioning over six months in individuals at clinical high risk for psychosis.Psychiatry Res 206, no. 2–3 (April 30, 2013): 195–99. https://doi.org/10.1016/j.psychres.2012.10.013.
Barbato M, Colijn MA, Keefe RSE, Perkins DO, Woods SW, Hawkins KA, et al. The course of cognitive functioning over six months in individuals at clinical high risk for psychosis. Psychiatry Res. 2013 Apr 30;206(2–3):195–9.
Barbato, Mariapaola, et al. “The course of cognitive functioning over six months in individuals at clinical high risk for psychosis.Psychiatry Res, vol. 206, no. 2–3, Apr. 2013, pp. 195–99. Pubmed, doi:10.1016/j.psychres.2012.10.013.
Barbato M, Colijn MA, Keefe RSE, Perkins DO, Woods SW, Hawkins KA, Christensen BK, Addington J. The course of cognitive functioning over six months in individuals at clinical high risk for psychosis. Psychiatry Res. 2013 Apr 30;206(2–3):195–199.
Journal cover image

Published In

Psychiatry Res

DOI

EISSN

1872-7123

Publication Date

April 30, 2013

Volume

206

Issue

2-3

Start / End Page

195 / 199

Location

Ireland

Related Subject Headings

  • Young Adult
  • Risk
  • Psychotic Disorders
  • Psychiatry
  • Prospective Studies
  • Prodromal Symptoms
  • Neuropsychological Tests
  • Male
  • Longitudinal Studies
  • Humans