Attentional and eye tracking deficits correlate with negative symptoms in schizophrenia.

Journal Article (Journal Article)

Thirty patients with a DSM-III-R diagnosis of schizophrenia were assessed for severity of schizophrenic symptoms using the Brief Psychiatric Rating Scale (BPRS) and were tested on a Continuous Performance Test (CPT) and a smooth pursuit eye tracking task. Negative symptoms were significantly correlated with eye tracking impairment (r = 0.43, p < 0.01) and CPT deficits (r = 0.67, p < 0.001), but performance on neither task was correlated with positive symptoms. CPT performance and eye tracking performance were modestly correlated with each other (r = 0.39, p < 0.01) and CPT performance was found to be a stronger predictor of negative symptoms than eye tracking performance. These data indicate that neurocognitive markers of vulnerability to schizophrenia are associated with negative rather than positive symptoms.

Full Text

Duke Authors

Cited Authors

  • Roitman, SE; Keefe, RS; Harvey, PD; Siever, LJ; Mohs, RC

Published Date

  • August 29, 1997

Published In

Volume / Issue

  • 26 / 2-3

Start / End Page

  • 139 - 146

PubMed ID

  • 9323344

International Standard Serial Number (ISSN)

  • 0920-9964

Digital Object Identifier (DOI)

  • 10.1016/s0920-9964(97)00044-3


  • eng

Conference Location

  • Netherlands