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Polycistronic vesicular stomatitis virus RNA transcripts.

Publication ,  Journal Article
Herman, RC; Schubert, M; Keene, JD; Lazzarini, RA
Published in: Proc Natl Acad Sci U S A
August 1980

A procedure to enrich for the sequences present at the junction between the linked messages in the polycistronic RNAs symthesized in vitro by vesicular stomatitis virus (VSV) is described. Analyses of these sequences show that they contain a precise transcript of both the intercistronic dinucleotide and the pentanucleotide 5'--C-U-G-U-U--3', common to the 5'-end of all VSV cistrons, covalently linked to the 3'-side of the intervening poly(A). The data strongly suggest that the VSV transcriptase polyadenylylates the mRNAs and can then resume direct and precise transcription of the genome-without reinitiation and without skipping nucleotides.

Duke Scholars

Published In

Proc Natl Acad Sci U S A

DOI

ISSN

0027-8424

Publication Date

August 1980

Volume

77

Issue

8

Start / End Page

4662 / 4665

Location

United States

Related Subject Headings

  • Vesicular stomatitis Indiana virus
  • Transcription, Genetic
  • RNA, Viral
  • RNA, Messenger
  • Poly A
  • Nucleic Acid Precursors
  • Genes, Viral
  • Genes
  • Base Sequence
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Herman, R. C., Schubert, M., Keene, J. D., & Lazzarini, R. A. (1980). Polycistronic vesicular stomatitis virus RNA transcripts. Proc Natl Acad Sci U S A, 77(8), 4662–4665. https://doi.org/10.1073/pnas.77.8.4662
Herman, R. C., M. Schubert, J. D. Keene, and R. A. Lazzarini. “Polycistronic vesicular stomatitis virus RNA transcripts.Proc Natl Acad Sci U S A 77, no. 8 (August 1980): 4662–65. https://doi.org/10.1073/pnas.77.8.4662.
Herman RC, Schubert M, Keene JD, Lazzarini RA. Polycistronic vesicular stomatitis virus RNA transcripts. Proc Natl Acad Sci U S A. 1980 Aug;77(8):4662–5.
Herman, R. C., et al. “Polycistronic vesicular stomatitis virus RNA transcripts.Proc Natl Acad Sci U S A, vol. 77, no. 8, Aug. 1980, pp. 4662–65. Pubmed, doi:10.1073/pnas.77.8.4662.
Herman RC, Schubert M, Keene JD, Lazzarini RA. Polycistronic vesicular stomatitis virus RNA transcripts. Proc Natl Acad Sci U S A. 1980 Aug;77(8):4662–4665.
Journal cover image

Published In

Proc Natl Acad Sci U S A

DOI

ISSN

0027-8424

Publication Date

August 1980

Volume

77

Issue

8

Start / End Page

4662 / 4665

Location

United States

Related Subject Headings

  • Vesicular stomatitis Indiana virus
  • Transcription, Genetic
  • RNA, Viral
  • RNA, Messenger
  • Poly A
  • Nucleic Acid Precursors
  • Genes, Viral
  • Genes
  • Base Sequence