Cancer genomics: integrating form and function.


Journal Article (Review)

The sequencing of the human genome has formed the foundation with which to develop technologies and reagents to perform true genome-scale biological studies. In particular, the development and increasing application of these high-throughput genome-scale technologies have fundamentally altered the way one can approach the analysis of cancer. It is now possible to imagine studies that interrogate the structure, expression and function of every gene in a comprehensive, highly parallel fashion, permitting the development of multidimensional, global views of cancer. In this review, we focus on recent advances in the application of genomic strategies to the study of cancer, with an emphasis on functional genomics and the prospects for integrating the knowledge gained from these approaches to further develop our understanding of cancer and design better therapeutic strategies.

Full Text

Duke Authors

Cited Authors

  • Kim, SY; Hahn, WC

Published Date

  • July 2007

Published In

Volume / Issue

  • 28 / 7

Start / End Page

  • 1387 - 1392

PubMed ID

  • 17434922

Pubmed Central ID

  • 17434922

International Standard Serial Number (ISSN)

  • 0143-3334

Digital Object Identifier (DOI)

  • 10.1093/carcin/bgm086


  • eng

Conference Location

  • England