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In vivo assessment of an absorbable and nonabsorbable knotless barbed suture for laparoscopic single-layer enterotomy closure: a clinical and biomechanical comparison against nonbarbed suture.

Publication ,  Journal Article
Omotosho, P; Yurcisin, B; Ceppa, E; Miller, J; Kirsch, D; Portenier, DD
Published in: J Laparoendosc Adv Surg Tech A
December 2011

BACKGROUND: Laparoscopic intracorporeal suturing and knot tying is a complex skill that requires repeated deliberate practice to master. A novel self-anchoring barbed suture material that does not require knot tying can eliminate knot failure and reduce operating time. The goal of this study was to compare the in vivo efficacy of two novel knotless barbed sutures (absorbable and nonabsorbable) for use with the Endo Stitch™ device (Covidien), against conventional suture (Endo Stitch device with Polysorb™ suture; Covidien) for laparoscopic closure of viscerotomies in canine stomach, jejunum, and colon. METHODS: Following Institutional Animal Care and Use Committee approval, 24 dogs underwent laparoscopic creation of 25-mm viscerotomies, three each in the stomach, jejunum, and colon. All viscerotomies were closed with the Endo Stitch device using the absorbable or nonabsorbable barbed suture or conventional suture. Closure time for each viscerotomy was recorded. Animals were survived for 3, 10, or 21 days, at which point the viscerotomies were burst-pressure tested. RESULTS: The closure leak rate in this study with 216 total viscerotomy closures was 0%. There was no statistically significant difference in mean burst pressure between viscerotomies closed with barbed suture versus control suture at any of the survival intervals. Barbed suture with the Endo Stitch device was associated with statistically significantly faster closure times than the control suture with the Endo Stitch device (P<.05), resulting in a reduction in closure time between 35% and 42%. CONCLUSION: This study reports the first use of barbed suture for the Endo Stitch device in laparoscopic gastrointestinal closure. The barbed suture for the Endo Stitch device is effective for laparoscopic single-layer gastrointestinal closure and is associated with a significantly reduced closure time.

Duke Scholars

Published In

J Laparoendosc Adv Surg Tech A

DOI

EISSN

1557-9034

Publication Date

December 2011

Volume

21

Issue

10

Start / End Page

893 / 897

Location

United States

Related Subject Headings

  • Sutures
  • Surgery
  • Pediatrics
  • Materials Testing
  • Laparoscopy
  • Dogs
  • Biomechanical Phenomena
  • Biocompatible Materials
  • Animals
  • 3202 Clinical sciences
 

Citation

APA
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ICMJE
MLA
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Omotosho, P., Yurcisin, B., Ceppa, E., Miller, J., Kirsch, D., & Portenier, D. D. (2011). In vivo assessment of an absorbable and nonabsorbable knotless barbed suture for laparoscopic single-layer enterotomy closure: a clinical and biomechanical comparison against nonbarbed suture. J Laparoendosc Adv Surg Tech A, 21(10), 893–897. https://doi.org/10.1089/lap.2011.0281
Omotosho, Philip, Basil Yurcisin, Eugene Ceppa, Jeffrey Miller, David Kirsch, and Dana D. Portenier. “In vivo assessment of an absorbable and nonabsorbable knotless barbed suture for laparoscopic single-layer enterotomy closure: a clinical and biomechanical comparison against nonbarbed suture.J Laparoendosc Adv Surg Tech A 21, no. 10 (December 2011): 893–97. https://doi.org/10.1089/lap.2011.0281.
Omotosho, Philip, et al. “In vivo assessment of an absorbable and nonabsorbable knotless barbed suture for laparoscopic single-layer enterotomy closure: a clinical and biomechanical comparison against nonbarbed suture.J Laparoendosc Adv Surg Tech A, vol. 21, no. 10, Dec. 2011, pp. 893–97. Pubmed, doi:10.1089/lap.2011.0281.
Journal cover image

Published In

J Laparoendosc Adv Surg Tech A

DOI

EISSN

1557-9034

Publication Date

December 2011

Volume

21

Issue

10

Start / End Page

893 / 897

Location

United States

Related Subject Headings

  • Sutures
  • Surgery
  • Pediatrics
  • Materials Testing
  • Laparoscopy
  • Dogs
  • Biomechanical Phenomena
  • Biocompatible Materials
  • Animals
  • 3202 Clinical sciences