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Reproducibility and beat-to-beat variability of digital echocardiograms

Publication ,  Journal Article
Wharton, WW; Donovan, CL; Hsieh, A; Collins, ME; Kisslo, JA; Ryan, T
Published in: Journal of the American Society of Echocardiography
December 1, 1997

To test the hypothesis that digital echocardiography (DE) is a reliable substitute for video tape (VT) for the interpretation of routine studies, we examined 51 pts with known or suspected cardiac disease. Images of the 4 standard views with and without color Doppler were recorded on VT and 4 separate digital studies were created: 3 sets of single cardiac cycle cine loops (SCCL) and 1 triple cardiac cycle cine loop (TCCL). All 5 recordings were analyzed separately by a single blinded observer for: 1) estimated LVEF, 2) wall motion score index (WMSI), 3) MR severity, 4) presence or absence of regional wall motion abnormalities (5 regions: ant, post, inf, lat, apical). The following were assessed: 1) variability among the 3 SCCL, 2) reproducibility of each SCCL compared to VT, 3) comparison between SCCL and TCCL (to test the advantages of longer loops). SCCL and TCCL correlated highly with VT for both WMSI (SCCL 1,2,3 vs VT r=.99; TCCL vs VT r=.99) and LVEF (SCCL1 vs VT r=.94; TCCL vs VT r=.93). Correlations among the 3 SCCL for WMSI were similarly high (r=.99 for all 3 pairs). Using VT as the standard, SCCL had an overall sensitivity of 97% and specificity 90% for the detection of abnormal wall motion. For individual regions (n=256), sensitivity ranged from 90% to 96% and specificity 91% to 100%. MR severity by DE was identical to VT in 36/51 pts, underestimated in 8 and over-estimated in 7 (in each case by 1 grade). In conclusion, 1) DE provides diagnoses that are highly correlated with standard VT, 2) beat-to-beat variability of SCCL is very low, 3) longer cine loops (3 cycles) offer no advantage over single cycle loops.

Duke Scholars

Published In

Journal of the American Society of Echocardiography

ISSN

0894-7317

Publication Date

December 1, 1997

Volume

10

Issue

4

Start / End Page

436

Related Subject Headings

  • Cardiovascular System & Hematology
  • 1102 Cardiorespiratory Medicine and Haematology
 

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Wharton, W. W., Donovan, C. L., Hsieh, A., Collins, M. E., Kisslo, J. A., & Ryan, T. (1997). Reproducibility and beat-to-beat variability of digital echocardiograms. Journal of the American Society of Echocardiography, 10(4), 436.
Wharton, W. W., C. L. Donovan, A. Hsieh, M. E. Collins, J. A. Kisslo, and T. Ryan. “Reproducibility and beat-to-beat variability of digital echocardiograms.” Journal of the American Society of Echocardiography 10, no. 4 (December 1, 1997): 436.
Wharton WW, Donovan CL, Hsieh A, Collins ME, Kisslo JA, Ryan T. Reproducibility and beat-to-beat variability of digital echocardiograms. Journal of the American Society of Echocardiography. 1997 Dec 1;10(4):436.
Wharton, W. W., et al. “Reproducibility and beat-to-beat variability of digital echocardiograms.” Journal of the American Society of Echocardiography, vol. 10, no. 4, Dec. 1997, p. 436.
Wharton WW, Donovan CL, Hsieh A, Collins ME, Kisslo JA, Ryan T. Reproducibility and beat-to-beat variability of digital echocardiograms. Journal of the American Society of Echocardiography. 1997 Dec 1;10(4):436.
Journal cover image

Published In

Journal of the American Society of Echocardiography

ISSN

0894-7317

Publication Date

December 1, 1997

Volume

10

Issue

4

Start / End Page

436

Related Subject Headings

  • Cardiovascular System & Hematology
  • 1102 Cardiorespiratory Medicine and Haematology