Skip to main content
Journal cover image

Hypotension during dobutamine stress echocardiography: is it related to dynamic intraventricular obstruction?

Publication ,  Journal Article
Heinle, SK; Tice, FD; Kisslo, J
Published in: Am Heart J
August 1995

Although it has been shown that a hypotensive response during dobutamine stress echocardiography is not a marker of coronary artery disease, the mechanism of this response remains unclear. We hypothesize that hypotension during dobutamine stress echocardiography is not related to the development of dynamic intraventricular obstruction. The development of left ventricular outflow obstruction was defined as a late-peaking Doppler velocity profile that exceeded baseline outflow velocity by at least 1 m/sec in 104 consecutive patients undergoing dobutamine stress echocardiography. Left ventricular outflow obstruction was seen in 13% of 15 patients with a hypotensive response (group 1) and in 13% of 89 patients without a hypotensive response (group 2). The mean baseline systolic blood pressure was 157 +/- 21 mm Hg in group 1 compared to 139 +/- 25 mm Hg in group 2 (p = 0.008). An ischemic response to dobutamine infusion as manifested by the development of new or worsening wall motion abnormalities was seen in 40% of group 1 patients and 34% of group 2 patients (p = 0.77). These data demonstrate that a hypotensive response is not related to the development of dynamic intraventricular obstruction during dobutamine stress echocardiography. Rather, there is a significant association between a higher baseline systolic blood pressure and a hypotensive response during dobutamine infusion.

Duke Scholars

Published In

Am Heart J

DOI

ISSN

0002-8703

Publication Date

August 1995

Volume

130

Issue

2

Start / End Page

314 / 317

Location

United States

Related Subject Headings

  • Ventricular Outflow Obstruction
  • Myocardial Contraction
  • Middle Aged
  • Male
  • Hypotension
  • Humans
  • Female
  • Exercise Test
  • Echocardiography, Doppler
  • Echocardiography
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Heinle, S. K., Tice, F. D., & Kisslo, J. (1995). Hypotension during dobutamine stress echocardiography: is it related to dynamic intraventricular obstruction? Am Heart J, 130(2), 314–317. https://doi.org/10.1016/0002-8703(95)90446-8
Heinle, S. K., F. D. Tice, and J. Kisslo. “Hypotension during dobutamine stress echocardiography: is it related to dynamic intraventricular obstruction?Am Heart J 130, no. 2 (August 1995): 314–17. https://doi.org/10.1016/0002-8703(95)90446-8.
Heinle, S. K., et al. “Hypotension during dobutamine stress echocardiography: is it related to dynamic intraventricular obstruction?Am Heart J, vol. 130, no. 2, Aug. 1995, pp. 314–17. Pubmed, doi:10.1016/0002-8703(95)90446-8.
Journal cover image

Published In

Am Heart J

DOI

ISSN

0002-8703

Publication Date

August 1995

Volume

130

Issue

2

Start / End Page

314 / 317

Location

United States

Related Subject Headings

  • Ventricular Outflow Obstruction
  • Myocardial Contraction
  • Middle Aged
  • Male
  • Hypotension
  • Humans
  • Female
  • Exercise Test
  • Echocardiography, Doppler
  • Echocardiography