Meeting the (N-terminal) end with acetylation.


Journal Article

Cell-fate decisions are tightly linked to cellular energy status. In this issue, Yi et al. (2011) introduce a mechanism by which Bcl-xL lowers the threshold for apoptosis by suppressing acetyl-CoA production, which, in turn, suppresses the N-alpha-acetylation important for activation of the proapoptotic protease caspase-2.

Full Text

Duke Authors

Cited Authors

  • Andersen, JL; Kornbluth, S

Published Date

  • August 2011

Published In

Volume / Issue

  • 146 / 4

Start / End Page

  • 503 - 505

PubMed ID

  • 21854977

Pubmed Central ID

  • 21854977

Electronic International Standard Serial Number (EISSN)

  • 1097-4172

International Standard Serial Number (ISSN)

  • 0092-8674

Digital Object Identifier (DOI)

  • 10.1016/j.cell.2011.07.024


  • eng