Not-so-pseudo a substrate: Acm1-mediated inhibition of the APC.

Journal Article (Journal Article)

In a recent issue of Molecular Cell, Enquist-Newman et al. (2008) demonstrate that Acm1 is ubiquitinated by APC(Cdc20). By contrast, the high-affinity interaction between Acm1 and APC(Cdh1) renders it a poor substrate, but a specific inhibitor, of the APC(Cdh1) complex.

Full Text

Duke Authors

Cited Authors

  • Wu, JQ; Kornbluth, S

Published Date

  • June 2008

Published In

Volume / Issue

  • 30 / 5

Start / End Page

  • 543 - 544

PubMed ID

  • 18538651

Electronic International Standard Serial Number (EISSN)

  • 1097-4164

International Standard Serial Number (ISSN)

  • 1097-2765

Digital Object Identifier (DOI)

  • 10.1016/j.molcel.2008.05.011


  • eng