Not-so-pseudo a substrate: Acm1-mediated inhibition of the APC.
Journal Article (Journal Article)
In a recent issue of Molecular Cell, Enquist-Newman et al. (2008) demonstrate that Acm1 is ubiquitinated by APC(Cdc20). By contrast, the high-affinity interaction between Acm1 and APC(Cdh1) renders it a poor substrate, but a specific inhibitor, of the APC(Cdh1) complex.
Full Text
Duke Authors
Cited Authors
- Wu, JQ; Kornbluth, S
Published Date
- June 2008
Published In
Volume / Issue
- 30 / 5
Start / End Page
- 543 - 544
PubMed ID
- 18538651
Electronic International Standard Serial Number (EISSN)
- 1097-4164
International Standard Serial Number (ISSN)
- 1097-2765
Digital Object Identifier (DOI)
- 10.1016/j.molcel.2008.05.011
Language
- eng