Novel tyrosine kinase identified by phosphotyrosine antibody screening of cDNA libraries.
In an attempt to clone protein tyrosine kinases, antiphosphotyrosine antibodies were used to screen lambda gt11 cDNA expression libraries. By this method, a 2.5-kilobase cDNA encoding a novel tyrosine kinase was isolated from a mouse liver cDNA library. This new gene is most closely related to the receptor tyrosine kinases ret, fms, and kit.
Kornbluth, S; Paulson, KE; Hanafusa, H
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