Can prenylcysteines be exploited as ligands for mammalian multidrug-resistance transporters?
Published
Journal Article (Review)
The overexpression of specific transport proteins in the membrane of many cancer cells renders these cells resistant to many therapeutic drugs. Some lipid-modified cysteine compounds inhibit one drug-transporting protein, indicating the potential of developing such compounds as therapeutic agents.
Full Text
Duke Authors
Cited Authors
- Hurwitz, LM; Casey, PJ
Published Date
- October 1997
Published In
Volume / Issue
- 4 / 10
Start / End Page
- 711 - 715
PubMed ID
- 9375248
Pubmed Central ID
- 9375248
International Standard Serial Number (ISSN)
- 1074-5521
Language
- eng
Conference Location
- United States