Quality control within the Asthma Clinical Research Network.

Published

Journal Article

Quality control and assurance are very important issues for multicenter clinical investigation. Although such investigation usually states that those factors are part of the investigation, at best this occurs to a minimal extent. Indeed, to ensure the best possible investigatory results with the least amount of variance between centers, the Asthma Clinical Research Network (ACRN) instituted strict written criteria that were continually overviewed. This article describes the ACRN's quality control of: clinic procedures and equipment, training and certification of study personnel, site visit evaluations, and the procedures of bronchoscopy and sputum induction. The examples given in this report demonstrate how various aspects of our investigation are performed.

Full Text

Cited Authors

  • Martin, RJ; Kephart, DK; Dyer, AM; Fahy, J; Kraft, M; Asthma Clinical Trials Network,

Published Date

  • December 2001

Published In

Volume / Issue

  • 22 / 6 Suppl

Start / End Page

  • 207S - 221S

PubMed ID

  • 11728625

Pubmed Central ID

  • 11728625

International Standard Serial Number (ISSN)

  • 0197-2456

Digital Object Identifier (DOI)

  • 10.1016/s0197-2456(01)00164-7

Language

  • eng