Biosynthesis of intervertebral disc matrix in vitro


Journal Article

Cells of the intervertebral disc express genes for aggrecan and collagen in an in vitro alginate culture system. Despite evidence for significant biosynthesis, the cells appear unable to assemble a mechanically functional matrix in this in vitro system.

Duke Authors

Cited Authors

  • Setton, LA; Baer, AE; Wang, JY; Kraus, VB

Published Date

  • December 1, 1999

Published In

Volume / Issue

  • 2 /

Start / End Page

  • 1325 -

International Standard Serial Number (ISSN)

  • 0589-1019

Citation Source

  • Scopus