Genetic analysis of regulatory mutants of alkaline phosphatase of E. coli.
Publication
, Journal Article
Kreuzer, K; Pratt, C; Torriani, A
Published in: Genetics
November 1975
A fine structure map of the phoR region of E. coli, mutations of which affect the rate of alkaline phosphatase synthesis, was constructed by Hfr X F- crosses. Mutations causing three different phenotypes (previously reported as phoRa, phoRb, phoRc (Garen and Echols 1962a,b) are clustered in three closely linked genetic loci. PhoR mutants of all three types, including the phoRb type not previously tested, are recessive to wild-type phoR+. In addition, phoRa and phoRc complement each other, while phoRa and phoRb do not. Our results support the hypothesis of Morris et al. (1974) that phoRc mutants represent a cistron (phoB) different from phoR.
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Published In
Genetics
DOI
ISSN
0016-6731
Publication Date
November 1975
Volume
81
Issue
3
Start / End Page
459 / 468
Location
United States
Related Subject Headings
- Mutation
- Genes, Regulator
- Genes, Dominant
- Escherichia coli
- Developmental Biology
- Chromosomes, Bacterial
- Chromosome Mapping
- Alkaline Phosphatase
- 3105 Genetics
- 3101 Biochemistry and cell biology
Citation
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Kreuzer, K., Pratt, C., & Torriani, A. (1975). Genetic analysis of regulatory mutants of alkaline phosphatase of E. coli. Genetics, 81(3), 459–468. https://doi.org/10.1093/genetics/81.3.459
Kreuzer, K., C. Pratt, and A. Torriani. “Genetic analysis of regulatory mutants of alkaline phosphatase of E. coli.” Genetics 81, no. 3 (November 1975): 459–68. https://doi.org/10.1093/genetics/81.3.459.
Kreuzer K, Pratt C, Torriani A. Genetic analysis of regulatory mutants of alkaline phosphatase of E. coli. Genetics. 1975 Nov;81(3):459–68.
Kreuzer, K., et al. “Genetic analysis of regulatory mutants of alkaline phosphatase of E. coli.” Genetics, vol. 81, no. 3, Nov. 1975, pp. 459–68. Pubmed, doi:10.1093/genetics/81.3.459.
Kreuzer K, Pratt C, Torriani A. Genetic analysis of regulatory mutants of alkaline phosphatase of E. coli. Genetics. 1975 Nov;81(3):459–468.
Published In
Genetics
DOI
ISSN
0016-6731
Publication Date
November 1975
Volume
81
Issue
3
Start / End Page
459 / 468
Location
United States
Related Subject Headings
- Mutation
- Genes, Regulator
- Genes, Dominant
- Escherichia coli
- Developmental Biology
- Chromosomes, Bacterial
- Chromosome Mapping
- Alkaline Phosphatase
- 3105 Genetics
- 3101 Biochemistry and cell biology