Prenatal dysthymia versus major depression effects on maternal cortisol and fetal growth.

Journal Article (Journal Article)

To determine differences between pregnant women diagnosed with Dysthymia versus Major Depression, depressed pregnant women (N=102) were divided by their diagnosis into Dysthymic (N=48) and Major Depression (N=54) groups and compared on self-report measures (depression, anxiety, anger, daily hassles and behavioral inhibition), on stress hormone levels (cortisol and norepinephrine), and on fetal measurements. The Major Depression group had more self-reported symptoms. However, the Dysthymic group had higher prenatal cortisol levels and lower fetal growth measurements (estimated weight, femur length, abdominal circumference) as measured at their first ultrasound (M=18 weeks gestation). Thus, depressed pregnant women with Dysthymia and Major Depression appeared to have different prenatal symptoms.

Full Text

Duke Authors

Cited Authors

  • Field, T; Diego, MA; Hernandez-Reif, M; Figueiredo, B; Ascencio, A; Schanberg, S; Kuhn, C

Published Date

  • 2008

Published In

Volume / Issue

  • 25 / 6

Start / End Page

  • E11 - E16

PubMed ID

  • 17587221

Electronic International Standard Serial Number (EISSN)

  • 1520-6394

Digital Object Identifier (DOI)

  • 10.1002/da.20307


  • eng

Conference Location

  • United States