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Racial and gender disparities and the role of primary tumor type on inpatient outcomes following craniotomy for brain metastases.

Publication ,  Journal Article
Nuño, M; Mukherjee, D; Elramsisy, A; Nosova, K; Lad, SP; Boakye, M; Yu, JS; Black, KL; Patil, CG
Published in: Ann Surg Oncol
August 2012

BACKGROUND: Race and gender disparities in outcomes have been documented in many cancers. Our study evaluated the role of race, gender, and tumor primary site in predicting in-hospital mortality, discharge disposition, and complications among patients with brain metastases. METHODS: Using Nationwide Inpatient Sample (NIS) data from 1998 to 2007, we evaluated in-patient outcomes of brain metastases patients who underwent a craniotomy in U.S. hospitals. Univariate and multivariate analyses were used to assess the effect of patient/tumor characteristics in predicting the proposed outcomes. RESULTS: NIS estimated 78,170 patients with metastatic brain tumors underwent craniotomy between 1998 and 2007 in the United States. Median age was 59.2 years, 52.1 % were women, and 6.4 % were black. In-hospital mortality rate was 2.2 % with an average length of stay of 7.6 days. Black patients had significantly higher morbidity and nonroutine discharges than whites/others (p < .0001). Black women had almost twice the mortality (3.4 vs 1.8 %, p < .0001), a higher complication rate (24.6 vs 18.8 %, p < .0001), longer hospital stays (10.0 vs 7.3 days, p < .0001), and more nonroutine discharges (45.1 vs 36.8 %, p < .0001), compared with white/other women. Tumor histology was a significant predictor of outcomes, with female lung cancer patients having the highest odds of mortality and primary gastrointestinal tumors having the highest number of complications. CONCLUSIONS: Evidence of race and gender disparities in outcomes were found in black patients, especially in black females who underwent surgical resection for brain metastases. These findings highlight an opportunity to reduce the gap of outcome disparities in brain metastasis patients.

Duke Scholars

Published In

Ann Surg Oncol

DOI

EISSN

1534-4681

Publication Date

August 2012

Volume

19

Issue

8

Start / End Page

2657 / 2663

Location

United States

Related Subject Headings

  • White People
  • United States
  • Survival Rate
  • Socioeconomic Factors
  • Sex Factors
  • Prognosis
  • Oncology & Carcinogenesis
  • Neoplasm Staging
  • Middle Aged
  • Male
 

Citation

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Chicago
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MLA
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Nuño, M., Mukherjee, D., Elramsisy, A., Nosova, K., Lad, S. P., Boakye, M., … Patil, C. G. (2012). Racial and gender disparities and the role of primary tumor type on inpatient outcomes following craniotomy for brain metastases. Ann Surg Oncol, 19(8), 2657–2663. https://doi.org/10.1245/s10434-012-2353-z
Nuño, Miriam, Debraj Mukherjee, Adam Elramsisy, Kristin Nosova, Shivanand P. Lad, Maxwell Boakye, John S. Yu, Keith L. Black, and Chirag G. Patil. “Racial and gender disparities and the role of primary tumor type on inpatient outcomes following craniotomy for brain metastases.Ann Surg Oncol 19, no. 8 (August 2012): 2657–63. https://doi.org/10.1245/s10434-012-2353-z.
Nuño M, Mukherjee D, Elramsisy A, Nosova K, Lad SP, Boakye M, et al. Racial and gender disparities and the role of primary tumor type on inpatient outcomes following craniotomy for brain metastases. Ann Surg Oncol. 2012 Aug;19(8):2657–63.
Nuño, Miriam, et al. “Racial and gender disparities and the role of primary tumor type on inpatient outcomes following craniotomy for brain metastases.Ann Surg Oncol, vol. 19, no. 8, Aug. 2012, pp. 2657–63. Pubmed, doi:10.1245/s10434-012-2353-z.
Nuño M, Mukherjee D, Elramsisy A, Nosova K, Lad SP, Boakye M, Yu JS, Black KL, Patil CG. Racial and gender disparities and the role of primary tumor type on inpatient outcomes following craniotomy for brain metastases. Ann Surg Oncol. 2012 Aug;19(8):2657–2663.
Journal cover image

Published In

Ann Surg Oncol

DOI

EISSN

1534-4681

Publication Date

August 2012

Volume

19

Issue

8

Start / End Page

2657 / 2663

Location

United States

Related Subject Headings

  • White People
  • United States
  • Survival Rate
  • Socioeconomic Factors
  • Sex Factors
  • Prognosis
  • Oncology & Carcinogenesis
  • Neoplasm Staging
  • Middle Aged
  • Male