Polarity and stratification of the epidermis.

Journal Article (Journal Article;Review)

Polarity is a fundamental property of epithelial cells. In this review, we discuss our current knowledge of the polarity of a stratified epithelium, the epidermis, focusing on similarities and differences with simple epithelial models. We highlight how the differences in tissue architecture and physiology result in alterations in some aspects of cell polarity. In addition, we discuss one of the most prominent uses for cell polarity in the epidermis-orienting the mitotic spindle to drive the stratification and differentiation of this tissue during development.

Full Text

Duke Authors

Cited Authors

  • Muroyama, A; Lechler, T

Published Date

  • October 2012

Published In

Volume / Issue

  • 23 / 8

Start / End Page

  • 890 - 896

PubMed ID

  • 22960184

Pubmed Central ID

  • PMC3549552

Electronic International Standard Serial Number (EISSN)

  • 1096-3634

Digital Object Identifier (DOI)

  • 10.1016/j.semcdb.2012.08.008


  • eng

Conference Location

  • England