Polarity and stratification of the epidermis

Journal Article

Polarity is a fundamental property of epithelial cells. In this review, we discuss our current knowledge of the polarity of a stratified epithelium, the epidermis, focusing on similarities and differences with simple epithelial models. We highlight how the differences in tissue architecture and physiology result in alterations in some aspects of cell polarity. In addition, we discuss one of the most prominent uses for cell polarity in the epidermis-orienting the mitotic spindle to drive the stratification and differentiation of this tissue during development. © 2012 Elsevier Ltd.

Full Text

Duke Authors

Cited Authors

  • Muroyama, A; Lechler, T

Published Date

  • 2012

Published In

Volume / Issue

  • 23 / 8

Start / End Page

  • 890 - 896

PubMed ID

  • 22960184

International Standard Serial Number (ISSN)

  • 1084-9521

Digital Object Identifier (DOI)

  • 10.1016/j.semcdb.2012.08.008