Using ordinal logistic regression to estimate the likelihood of colorectal neoplasia.


Journal Article

The utility of ordinal logistic regression in the prediction of colorectal neoplasia was demonstrated in a group of 461 consecutive patients undergoing colonoscopy in a community practice. One hundred twenty-nine patients had adenomatous polyps and 34 had colorectal adenocarcinoma. An ordinal logistic regression model developed in a random subset (292 patients) identified five predictors of colorectal neoplasia. Colorectal neoplasia risk could be predicted using the patient's age, sex, hematocrit, fecal occult blood test result and indication for colonoscopy. The risk of colorectal neoplasia in the remaining subset of patients (169) could be reliably estimated from the model. Ordinal logistic regression analysis in this select group of patients can accurately estimate the likelihood of colorectal neoplasia. Because the generalizability of our findings are unknown, the model should not be applied to other patients. However, application of this technique to an unselected group of patients not already referred for colonoscopy could provide unbiased estimates of colorectal neoplasia risk in individual patients.

Full Text

Duke Authors

Cited Authors

  • Brazer, SR; Pancotto, FS; Long, TT; Harrell, FE; Lee, KL; Tyor, MP; Pryor, DB

Published Date

  • 1991

Published In

Volume / Issue

  • 44 / 11

Start / End Page

  • 1263 - 1270

PubMed ID

  • 1941020

Pubmed Central ID

  • 1941020

International Standard Serial Number (ISSN)

  • 0895-4356

Digital Object Identifier (DOI)

  • 10.1016/0895-4356(91)90159-7


  • eng

Conference Location

  • United States