Skip to main content
Journal cover image

Assessment of regional left ventricular function using gated radionuclide angiography.

Publication ,  Journal Article
Gibbons, RJ; Morris, KG; Lee, K; Coleman, RE; Cobb, FR
Published in: Am J Cardiol
August 1, 1984

A simple method for the assessment of regional left ventricular (LV) function using gated radionuclide angiography is described. The method divides the LV region of interest in the left anterior oblique view into quadrants using a count-weighted center point and a transparent overlay. The regional ejection fraction (EF) was determined at rest and during upright bicycle exercise for each of 3 quadrants identified as posterior, septal and apical. The study group consisted of 50 patients with chest pain. Nine of these patients had normal coronary arteries and 41 had significant coronary artery disease (CAD). Regional EF measurements were highly reproducible at rest and exercise in all regions. Regional EF values at rest were compared with the subjective assessment of wall motion on the contrast ventriculogram and were significantly lower in regions with abnormal wall motion. Regional EF increased with exercise in all patients with normal coronary arteries. In patients with CAD and normal regional wall motion at rest, the regional exercise response was significantly more sensitive (p = 0.004) than global exercise response and marginally more sensitive (p = 0.06) than the subjective assessment of exercise wall motion on visual radionuclide images in the diagnosis of CAD. These results suggest that the measurement of regional LV function may be useful in the noninvasive diagnosis of CAD.

Duke Scholars

Published In

Am J Cardiol

DOI

ISSN

0002-9149

Publication Date

August 1, 1984

Volume

54

Issue

3

Start / End Page

294 / 300

Location

United States

Related Subject Headings

  • Stroke Volume
  • Radionuclide Imaging
  • Radiography
  • Middle Aged
  • Male
  • Humans
  • Heart Ventricles
  • Heart
  • Exercise Test
  • Coronary Disease
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Gibbons, R. J., Morris, K. G., Lee, K., Coleman, R. E., & Cobb, F. R. (1984). Assessment of regional left ventricular function using gated radionuclide angiography. Am J Cardiol, 54(3), 294–300. https://doi.org/10.1016/0002-9149(84)90186-3
Gibbons, R. J., K. G. Morris, K. Lee, R. E. Coleman, and F. R. Cobb. “Assessment of regional left ventricular function using gated radionuclide angiography.Am J Cardiol 54, no. 3 (August 1, 1984): 294–300. https://doi.org/10.1016/0002-9149(84)90186-3.
Gibbons RJ, Morris KG, Lee K, Coleman RE, Cobb FR. Assessment of regional left ventricular function using gated radionuclide angiography. Am J Cardiol. 1984 Aug 1;54(3):294–300.
Gibbons, R. J., et al. “Assessment of regional left ventricular function using gated radionuclide angiography.Am J Cardiol, vol. 54, no. 3, Aug. 1984, pp. 294–300. Pubmed, doi:10.1016/0002-9149(84)90186-3.
Gibbons RJ, Morris KG, Lee K, Coleman RE, Cobb FR. Assessment of regional left ventricular function using gated radionuclide angiography. Am J Cardiol. 1984 Aug 1;54(3):294–300.
Journal cover image

Published In

Am J Cardiol

DOI

ISSN

0002-9149

Publication Date

August 1, 1984

Volume

54

Issue

3

Start / End Page

294 / 300

Location

United States

Related Subject Headings

  • Stroke Volume
  • Radionuclide Imaging
  • Radiography
  • Middle Aged
  • Male
  • Humans
  • Heart Ventricles
  • Heart
  • Exercise Test
  • Coronary Disease