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The superfamily of heptahelical receptors.

Publication ,  Journal Article
Lefkowitz, RJ
Published in: Nat Cell Biol
July 2000

Despite a growing appreciation of functional analogies between visual and hormonal signalling systems in the early 1980s, the discovery of the close structural relationship between rhodopsin and the beta2-adrenergic receptor, and of the existence of a larger 'superfamily' of such receptors, came as a total surprise. Here I provide a personal perspective on events leading up to and flowing from this exciting discovery that opened up a vast field of research.

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Published In

Nat Cell Biol

DOI

ISSN

1465-7392

Publication Date

July 2000

Volume

2

Issue

7

Start / End Page

E133 / E136

Location

England

Related Subject Headings

  • Vision, Ocular
  • Second Messenger Systems
  • Rhodopsin
  • Receptors, Adrenergic, beta
  • Mutation
  • Humans
  • Hormones
  • History, 20th Century
  • Heterotrimeric GTP-Binding Proteins
  • Developmental Biology
 

Citation

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Lefkowitz, R. J. (2000). The superfamily of heptahelical receptors. Nat Cell Biol, 2(7), E133–E136. https://doi.org/10.1038/35017152
Lefkowitz, R. J. “The superfamily of heptahelical receptors.Nat Cell Biol 2, no. 7 (July 2000): E133–36. https://doi.org/10.1038/35017152.
Lefkowitz RJ. The superfamily of heptahelical receptors. Nat Cell Biol. 2000 Jul;2(7):E133–6.
Lefkowitz, R. J. “The superfamily of heptahelical receptors.Nat Cell Biol, vol. 2, no. 7, July 2000, pp. E133–36. Pubmed, doi:10.1038/35017152.
Lefkowitz RJ. The superfamily of heptahelical receptors. Nat Cell Biol. 2000 Jul;2(7):E133–E136.

Published In

Nat Cell Biol

DOI

ISSN

1465-7392

Publication Date

July 2000

Volume

2

Issue

7

Start / End Page

E133 / E136

Location

England

Related Subject Headings

  • Vision, Ocular
  • Second Messenger Systems
  • Rhodopsin
  • Receptors, Adrenergic, beta
  • Mutation
  • Humans
  • Hormones
  • History, 20th Century
  • Heterotrimeric GTP-Binding Proteins
  • Developmental Biology