The superfamily of heptahelical receptors.

Published

Journal Article

Despite a growing appreciation of functional analogies between visual and hormonal signalling systems in the early 1980s, the discovery of the close structural relationship between rhodopsin and the beta2-adrenergic receptor, and of the existence of a larger 'superfamily' of such receptors, came as a total surprise. Here I provide a personal perspective on events leading up to and flowing from this exciting discovery that opened up a vast field of research.

Full Text

Duke Authors

Cited Authors

  • Lefkowitz, RJ

Published Date

  • July 2000

Published In

Volume / Issue

  • 2 / 7

Start / End Page

  • E133 - E136

PubMed ID

  • 10878827

Pubmed Central ID

  • 10878827

Electronic International Standard Serial Number (EISSN)

  • 1476-4679

International Standard Serial Number (ISSN)

  • 1465-7392

Digital Object Identifier (DOI)

  • 10.1038/35017152

Language

  • eng