Direct binding studies of adrenergic receptors: biochemical, physiologic, and clinical implications.

Published

Journal Article (Review)

Recently developed radioligand binding techniques permit direct investigation of the alpha- and beta-adrenergic receptors for catecholamines in a wide variety of tissues. These techniques allow the receptors to be quantitated, characterized, and studied under varying conditions of physiologic and pathophysiologic interest. They are providing fresh insights into the mechanisms by which endogenous catecholamines and other hormones regulate the properties of the adrenergic receptors and, in turn, control tissue sensitivity to catecholamine action.

Full Text

Duke Authors

Cited Authors

  • Lefkowitz, RJ

Published Date

  • September 1, 1979

Published In

Volume / Issue

  • 91 / 3

Start / End Page

  • 450 - 458

PubMed ID

  • 38720

Pubmed Central ID

  • 38720

International Standard Serial Number (ISSN)

  • 0003-4819

Digital Object Identifier (DOI)

  • 10.7326/0003-4819-91-3-450

Language

  • eng

Conference Location

  • United States