Subacute combined degeneration due to copper deficiency.

Journal Article (Journal Article)

There is growing clinical evidence supporting a connection between copper deficiency and subacute combined degeneration. While nearly half of patients with copper deficiency myelopathy exhibit MRI abnormalities, signal changes are often ill-defined in distribution. We report a patient with sensory ataxia and spastic paraplegia from copper deficiency whose MRI demonstrates abnormal signal restricted to the dorsal and lateral columns, providing clear radiological support of an association between hypocupremia and combined system degeneration.

Full Text

Duke Authors

Cited Authors

  • Ferrara, JM; Skeen, MB; Edwards, NJ; Gray, L; Massey, EW

Published Date

  • October 2007

Published In

Volume / Issue

  • 17 / 4

Start / End Page

  • 375 - 377

PubMed ID

  • 17894634

International Standard Serial Number (ISSN)

  • 1051-2284

Digital Object Identifier (DOI)

  • 10.1111/j.1552-6569.2007.00126.x


  • eng

Conference Location

  • United States