Intracerebral hemorrhage outcome: apolipoprotein E genotype, hematoma, and edema volumes.

Journal Article (Journal Article)

We investigated whether early hematoma or edema volumes could explain the adverse association between APOE epsilon4 and survival in intracerebral hemorrhage. Among 102 patients, epsilon4 carriers had a higher mortality rate than non-epsilon4 carriers (38 versus 24%, p = 0.05). Nonsurvivors had larger hematoma (75.5 cm3 versus 27.1 cm3, p<0.001) and edema volumes (37.5 cm3 versus 17.1 cm3, p<0.01), but these were not associated with epsilon4 after adjusting for race, age, and type of hemorrhage.

Full Text

Duke Authors

Cited Authors

  • McCarron, MO; Hoffmann, KL; DeLong, DM; Gray, L; Saunders, AM; Alberts, MJ

Published Date

  • December 10, 1999

Published In

Volume / Issue

  • 53 / 9

Start / End Page

  • 2176 - 2179

PubMed ID

  • 10599801

International Standard Serial Number (ISSN)

  • 0028-3878

Digital Object Identifier (DOI)

  • 10.1212/wnl.53.9.2176

Language

  • eng

Conference Location

  • United States