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High-dose gadolinium-enhanced MRI for diagnosis of meningeal metastases.

Publication ,  Journal Article
Kallmes, DF; Gray, L; Glass, JP
Published in: Neuroradiology
January 1998

We compared high-dose (0.3 mmol/kg) and standard-dose (0.1 mmol/kg) gadolinium-enhanced MRI for diagnosis of meningeal metastases in 12 patients with suspected meningeal metastases. They were imaged with both standard-dose and high-dose gadolinium. All patients with abnormal meningeal enhancement underwent at least one lumber puncture for cerebrospinal fluid (CSF) cytology, while patients with normal meningeal enhancement were followed clinically. All patients with negative CSF cytology also were followed clinically. A single observer reviewed all the images, with specific attention to the enhancement pattern of the meninges. Abnormal leptomeningeal enhancement was present in three cases, and abnormal pachymeningeal enhancement in three other patients. All of these patients had abnormal CSF analyses. In two of the three cases of abnormal leptomeningeal enhancement the disease was more evident on high-dose than on standard-dose imaging; in one case the abnormal enhancement was visible only on high-dose imaging. In one of the three cases with abnormal pachymeningeal enhancement, the disease was evident prospectively only with high-dose imaging.

Duke Scholars

Published In

Neuroradiology

DOI

ISSN

0028-3940

Publication Date

January 1998

Volume

40

Issue

1

Start / End Page

23 / 26

Location

Germany

Related Subject Headings

  • Spinal Puncture
  • Predictive Value of Tests
  • Nuclear Medicine & Medical Imaging
  • Middle Aged
  • Meninges
  • Meningeal Neoplasms
  • Male
  • Magnetic Resonance Imaging
  • Humans
  • Gadolinium
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Kallmes, D. F., Gray, L., & Glass, J. P. (1998). High-dose gadolinium-enhanced MRI for diagnosis of meningeal metastases. Neuroradiology, 40(1), 23–26. https://doi.org/10.1007/s002340050532
Kallmes, D. F., L. Gray, and J. P. Glass. “High-dose gadolinium-enhanced MRI for diagnosis of meningeal metastases.Neuroradiology 40, no. 1 (January 1998): 23–26. https://doi.org/10.1007/s002340050532.
Kallmes DF, Gray L, Glass JP. High-dose gadolinium-enhanced MRI for diagnosis of meningeal metastases. Neuroradiology. 1998 Jan;40(1):23–6.
Kallmes, D. F., et al. “High-dose gadolinium-enhanced MRI for diagnosis of meningeal metastases.Neuroradiology, vol. 40, no. 1, Jan. 1998, pp. 23–26. Pubmed, doi:10.1007/s002340050532.
Kallmes DF, Gray L, Glass JP. High-dose gadolinium-enhanced MRI for diagnosis of meningeal metastases. Neuroradiology. 1998 Jan;40(1):23–26.
Journal cover image

Published In

Neuroradiology

DOI

ISSN

0028-3940

Publication Date

January 1998

Volume

40

Issue

1

Start / End Page

23 / 26

Location

Germany

Related Subject Headings

  • Spinal Puncture
  • Predictive Value of Tests
  • Nuclear Medicine & Medical Imaging
  • Middle Aged
  • Meninges
  • Meningeal Neoplasms
  • Male
  • Magnetic Resonance Imaging
  • Humans
  • Gadolinium