Genetic and neurobiological basis of alcohol-seeking behavior

Journal Article

Through selective breeding, rat lines exhibiting high and low alcohol drinking preference have been developed as useful animal models for studying the neurobiological basis of alcohol-seeking behavior. The identified differences between lines in neurotransmitter functioning allows the evaluation of receptor agonist/antagonist compounds that might be efficacious in the treatment of alcohol craving and dependence.

Cited Authors

  • Li, TK; Lumeng, L; McBride, WJ; Murphy, JM

Published Date

  • 1994

Published In

  • Alcohol and Alcoholism

Volume / Issue

  • 29 / 6

Start / End Page

  • 697 - 700