Transcranial magnetic stimulation: applications in basic neuroscience and neuropsychopharmacology.

Journal Article (Journal Article)

Introduced 15 years ago, transcranial magnetic stimulation (TMS) is a non-invasive means of stimulating the cortex that has proved to be a unique tool for probing brain-behaviour relationships. While a therapeutic role for TMS in neuropsychiatry is uncertain, the utility of TMS in studying brain function has been demonstrated in diverse neuroscience applications. We review studies in animals on the mechanisms of action of TMS, and present a summary of the applications of TMS in basic neuroscience. TMS is still a relatively young technique, and unanswered questions remain regarding its acute and chronic impact on neural excitability and various aspects of brain function. Nonetheless, recent work with TMS has demonstrated its unique role in complementing other tools for studying brain function. As a brain intervention tool, TMS holds the promise of moving beyond correlative studies to help define the functional role of cortical regions in selected cognitive and affective processes.

Full Text

Duke Authors

Cited Authors

  • Lisanby, SH; Luber, B; Perera, T; Sackeim, HA

Published Date

  • September 2000

Published In

Volume / Issue

  • 3 / 3

Start / End Page

  • 259 - 273

PubMed ID

  • 11343603

Electronic International Standard Serial Number (EISSN)

  • 1469-5111

Digital Object Identifier (DOI)

  • 10.1017/S1461145700002005


  • eng

Conference Location

  • England