Neural recordings and behavioral observations in the monkey vestibulo-ocular reflex constrain the cellular mechanisms for cerebellum-dependent behavioral learning.

Journal Article (Journal Article)

Recordings from the cerebellum under behavioral conditions that cause learning in the vestibulo-ocular reflex (VOR) constrain the cellular mechanisms that could mediate learning. Analysis of the complex-spike responses of Purkinje cells demonstrates a mismatch between the properties of cerebellar long-term depression (LTD) in vitro and the signals available to guide learning in vivo. To resolve this mismatch, it may be necessary to assume that there are multiple cellular mechanisms of VOR learning, including both depression and potentiation.

Full Text

Duke Authors

Cited Authors

  • Lisberger, SG; Raymond, JL

Published Date

  • 1996

Published In

Volume / Issue

  • 90 / 5-6

Start / End Page

  • 381 - 382

PubMed ID

  • 9089517

International Standard Serial Number (ISSN)

  • 0928-4257

Digital Object Identifier (DOI)

  • 10.1016/s0928-4257(97)87923-5


  • eng

Conference Location

  • France