Vestibular inputs to brain stem neurons that participate in motor learning in the primate vestibuloocular reflex.


Journal Article

1. Previous studies have described a subpopulation of interneurons in the vestibuloocular reflex (VOR) pathways that express large changes in their responses to head turns in conjunction with motor learning in the VOR. These neurons are called flocculus target neurons (FTNs) because they are inhibited at monosynaptic latencies by stimulation of the flocculus and ventral paraflocculus. 2. Electrical stimulation of the vestibular labyrinth revealed that FTNs receive excitatory monosynaptic inputs from the ipsilateral vestibular labyrinth and longer-latency, excitatory inputs from the contralateral labyrinth. 3. Our data show that commissural inhibition, which has been thought to be an important feature of vestibular processing, does not provide the dominant inputs from the contralateral labyrinth to FTNs. Instead, the inputs from both labyrinths are excitatory and may be functionally antagonistic. Changes in the balance of excitatory inputs from the two horizontal canals to FTNs could contribute to motor learning in the VOR.

Full Text

Duke Authors

Cited Authors

  • Broussard, DM; Lisberger, SG

Published Date

  • November 1992

Published In

Volume / Issue

  • 68 / 5

Start / End Page

  • 1906 - 1909

PubMed ID

  • 1479453

Pubmed Central ID

  • 1479453

International Standard Serial Number (ISSN)

  • 0022-3077

Digital Object Identifier (DOI)

  • 10.1152/jn.1992.68.5.1906


  • eng

Conference Location

  • United States