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Osteoporosis considerations in the frail elderly.

Publication ,  Journal Article
Suh, TT; Lyles, KW
Published in: Curr Opin Rheumatol
July 2003

Osteoporosis is a growing public health problem throughout the world, in part because of the increasing numbers of people living beyond the age of 65 years. Skeletal fractures are the clinical manifestation of the disease, with older patients the most severely affected. Conditions associated with frailty such as falls and reduced muscle strength likely contribute to fractures, causing substantial mortality, morbidity, and economic cost. Screening guidelines for osteoporosis have been issued recently and take into account multiple risk factors for this condition. Falls are the chief mechanism by which osteoporotic fractures occur. Nonpharmacologic interventions for osteoporosis mainly address fall and frailty prevention, whereas pharmacologic interventions target bone loss through decreasing bone resorption, increasing bone formation, or a combination of both processes. Although guidelines for intervention strategies are in flux, it is now suggested that absolute fracture risk rather than diagnostic thresholds be used to determine the timing for therapeutic intervention. Individual risks and benefits of therapies need to be considered before choosing a therapeutic regimen.

Duke Scholars

Published In

Curr Opin Rheumatol

DOI

ISSN

1040-8711

Publication Date

July 2003

Volume

15

Issue

4

Start / End Page

481 / 486

Location

United States

Related Subject Headings

  • Osteoporosis
  • Male
  • Humans
  • Frail Elderly
  • Fractures, Spontaneous
  • Female
  • Arthritis & Rheumatology
  • Aged
  • 3202 Clinical sciences
  • 1103 Clinical Sciences
 

Citation

APA
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ICMJE
MLA
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Suh, T. T., & Lyles, K. W. (2003). Osteoporosis considerations in the frail elderly. Curr Opin Rheumatol, 15(4), 481–486. https://doi.org/10.1097/00002281-200307000-00018
Suh, Theodore T., and Kenneth W. Lyles. “Osteoporosis considerations in the frail elderly.Curr Opin Rheumatol 15, no. 4 (July 2003): 481–86. https://doi.org/10.1097/00002281-200307000-00018.
Suh TT, Lyles KW. Osteoporosis considerations in the frail elderly. Curr Opin Rheumatol. 2003 Jul;15(4):481–6.
Suh, Theodore T., and Kenneth W. Lyles. “Osteoporosis considerations in the frail elderly.Curr Opin Rheumatol, vol. 15, no. 4, July 2003, pp. 481–86. Pubmed, doi:10.1097/00002281-200307000-00018.
Suh TT, Lyles KW. Osteoporosis considerations in the frail elderly. Curr Opin Rheumatol. 2003 Jul;15(4):481–486.

Published In

Curr Opin Rheumatol

DOI

ISSN

1040-8711

Publication Date

July 2003

Volume

15

Issue

4

Start / End Page

481 / 486

Location

United States

Related Subject Headings

  • Osteoporosis
  • Male
  • Humans
  • Frail Elderly
  • Fractures, Spontaneous
  • Female
  • Arthritis & Rheumatology
  • Aged
  • 3202 Clinical sciences
  • 1103 Clinical Sciences