Colloidal gold fluorescent microspheres: a new retrograde marker visualized by light and electron microscopy.

Journal Article (Journal Article)

A new retrograde tracer, rhodamine latex microspheres, permits labeled neurons to be visualized with fluorescence light microscopy. However, their use has been limited to the light microscope. We now have developed colloidal gold fluorescent microspheres which identify retrogradely labeled neurons first by fluorescence microscopy and then by electron microscopy. This new fluorescent/EM tracer will find widespread use in the field of neuroscience to elucidate the ultrastructural integrity of neuronal networks.

Full Text

Duke Authors

Cited Authors

  • Quattrochi, JJ; Madison, R; Sidman, RL; Kljavin, I

Published Date

  • April 1, 1987

Published In

Volume / Issue

  • 96 / 1

Start / End Page

  • 219 - 224

PubMed ID

  • 3556514

International Standard Serial Number (ISSN)

  • 0014-4886

Digital Object Identifier (DOI)

  • 10.1016/0014-4886(87)90184-1


  • eng

Conference Location

  • United States