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Lephetamine abuse and dependence: clinical effects and withdrawal syndrome.

Publication ,  Journal Article
Janiri, L; Mannelli, P; Pirrongelli, C; Lo Monaco, M; Tempesta, E
Published in: Br J Addict
January 1989

Lephetamine (L-SPA) is a compound with central analgesic and anti-inflammatory action, recently reported to be abused in Italy. In this study, cases of L-SPA abuse were recorded. The survey included 15 patients who were assessed for effects caused by using L-SPA and induced by withdrawal. Moreover L-SPA was administered to 15 volunteers. L-SPA displayed effects partly similar to opiates and its withdrawal caused both subjective and objective symptoms. It is concluded that L-SPA exhibits abuse liability and dependence potential of a certain degree.

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Published In

Br J Addict

DOI

ISSN

0952-0481

Publication Date

January 1989

Volume

84

Issue

1

Start / End Page

89 / 95

Location

England

Related Subject Headings

  • Substance-Related Disorders
  • Substance Withdrawal Syndrome
  • Phenethylamines
  • Male
  • Female
 

Citation

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Janiri, L., Mannelli, P., Pirrongelli, C., Lo Monaco, M., & Tempesta, E. (1989). Lephetamine abuse and dependence: clinical effects and withdrawal syndrome. Br J Addict, 84(1), 89–95. https://doi.org/10.1111/j.1360-0443.1989.tb00555.x
Janiri, L., P. Mannelli, C. Pirrongelli, M. Lo Monaco, and E. Tempesta. “Lephetamine abuse and dependence: clinical effects and withdrawal syndrome.Br J Addict 84, no. 1 (January 1989): 89–95. https://doi.org/10.1111/j.1360-0443.1989.tb00555.x.
Janiri L, Mannelli P, Pirrongelli C, Lo Monaco M, Tempesta E. Lephetamine abuse and dependence: clinical effects and withdrawal syndrome. Br J Addict. 1989 Jan;84(1):89–95.
Janiri, L., et al. “Lephetamine abuse and dependence: clinical effects and withdrawal syndrome.Br J Addict, vol. 84, no. 1, Jan. 1989, pp. 89–95. Pubmed, doi:10.1111/j.1360-0443.1989.tb00555.x.
Janiri L, Mannelli P, Pirrongelli C, Lo Monaco M, Tempesta E. Lephetamine abuse and dependence: clinical effects and withdrawal syndrome. Br J Addict. 1989 Jan;84(1):89–95.

Published In

Br J Addict

DOI

ISSN

0952-0481

Publication Date

January 1989

Volume

84

Issue

1

Start / End Page

89 / 95

Location

England

Related Subject Headings

  • Substance-Related Disorders
  • Substance Withdrawal Syndrome
  • Phenethylamines
  • Male
  • Female