Psychosocial treatment strategies in the MTA study: rationale, methods, and critical issues in design and implementation.

Published

Journal Article

The Collaborative Multimodal Treatment Study of Children with Attention Deficit Hyperactivity Disorder (ADHD), the MTA, is the first multisite, cooperative agreement treatment study of children, and the largest psychiatric/psychological treatment trial ever conducted by the National Institute of Mental Health. It examines the effectiveness of Medication vs. Psychosocial treatment vs. their combination for treatment of ADHD and compares these experimental arms to each other and to routine community care. In a parallel group design, 579 (male and female) ADHD children, aged 7-9 years, 11 months, were randomly assigned to one of the four experimental arms, and then received 14 months of prescribed treatment (or community care) with periodic reassessments. After delineating the theoretical and empirical rationales for Psychosocial treatment of ADHD, we describe the MTA's Psychosocial Treatment strategy applied to all children in two of the four experimental arms (Psychosocial treatment alone; Combined treatment). Psychosocial treatment consisted of three major components: a Parent Training component, a two-part School Intervention component, and a child treatment component anchored in an intensive Summer Treatment Program. Components were selected based on evidence of treatment efficacy and because they address comprehensive symptom targets, settings, comorbidities, and functional domains. We delineate key conceptual and logistical issues faced by clinical researchers in design and implementation of Psychosocial research with examples of how these issues were addressed in the MTA study.

Full Text

Duke Authors

Cited Authors

  • Wells, KC; Pelham, WE; Kotkin, RA; Hoza, B; Abikoff, HB; Abramowitz, A; Arnold, LE; Cantwell, DP; Conners, CK; Del Carmen, R; Elliott, G; Greenhill, LL; Hechtman, L; Hibbs, E; Hinshaw, SP; Jensen, PS; March, JS; Swanson, JM; Schiller, E

Published Date

  • December 2000

Published In

Volume / Issue

  • 28 / 6

Start / End Page

  • 483 - 505

PubMed ID

  • 11104313

Pubmed Central ID

  • 11104313

Electronic International Standard Serial Number (EISSN)

  • 1573-2835

International Standard Serial Number (ISSN)

  • 0091-0627

Digital Object Identifier (DOI)

  • 10.1023/a:1005174913412

Language

  • eng