An EcoRI RFLP in the 5' region of the human NF1 gene.

Journal Article (Journal Article)

Von Recklinghausen neurofibromatosis or type 1 neurofibromatosis (NF1), is one of the most common autosomal dominant disorders. NF1 is characterized by neurofibromas, café-au-lait spots and Lisch nodules of the iris. The NF1 gene is located in 17q11.2. The restriction fragment length polymorphism reported here will be useful in linkage analysis in NF1 families.

Full Text

Duke Authors

Cited Authors

  • Reyniers, E; De Boulle, K; Marchuk, DA; Andersen, LB; Collins, FS; Willems, PJ

Published Date

  • December 1993

Published In

Volume / Issue

  • 92 / 6

Start / End Page

  • 631 -

PubMed ID

  • 7903272

International Standard Serial Number (ISSN)

  • 0340-6717

Digital Object Identifier (DOI)

  • 10.1007/BF00420953


  • eng

Conference Location

  • Germany