Interferometric Synthetic Aperture Microscopy: Tissue structure inferred by computed imaging techniques


Journal Article

Interferometric Synthetic Aperture Microscopy (ISAM)1 is an optical microscopy computed-imaging technique for measuring the optical properties of three-dimensional structures and biological tissues. In this work, the principle of ISAM is reviewed, and its application to imaging tissue properties in various scanning geometries and instrument configurations is explored. The practicality of ISAM is demonstrated by imaging a rat heart and muscle using a real-time implementation of ISAM in conjunction with a clinical cart Optical Coherence Tomography instrument.

Full Text

Duke Authors

Cited Authors

  • Marks, DL; Ralston, TS; Davis, BJ; Carney, PS; Boppart, SA

Published Date

  • April 21, 2008

Published In

Volume / Issue

  • 6864 /

International Standard Serial Number (ISSN)

  • 1605-7422

Digital Object Identifier (DOI)

  • 10.1117/12.763390

Citation Source

  • Scopus