Nonlinear interferometric vibrational imaging.


Journal Article

Coherent anti-Stokes Raman scattering (CARS) processes are "coherent," but the phase of the anti-Stokes radiation is lost by most incoherent spectroscopic CARS measurements. We propose a Raman microscopy imaging method called nonlinear interferometric vibrational imaging, which measures Raman spectra by obtaining the temporal anti-Stokes signal through nonlinear interferometry. With a more complete knowledge of the anti-Stokes signal, we show through simulations that a high-resolution Raman spectrum can be obtained of a molecule in a single pulse using broad band radiation. This could be useful for identifying the three-dimensional spatial distribution of molecular species in tissue.

Full Text

Duke Authors

Cited Authors

  • Marks, DL; Boppart, SA

Published Date

  • March 25, 2004

Published In

Volume / Issue

  • 92 / 12

Start / End Page

  • 123905 -

PubMed ID

  • 15089675

Pubmed Central ID

  • 15089675

Electronic International Standard Serial Number (EISSN)

  • 1079-7114

International Standard Serial Number (ISSN)

  • 0031-9007

Digital Object Identifier (DOI)

  • 10.1103/physrevlett.92.123905


  • eng