Protein S-nitrosylation: purview and parameters.

Published

Journal Article (Review)

S-nitrosylation, the covalent attachment of a nitrogen monoxide group to the thiol side chain of cysteine, has emerged as an important mechanism for dynamic, post-translational regulation of most or all main classes of protein. S-nitrosylation thereby conveys a large part of the ubiquitous influence of nitric oxide (NO) on cellular signal transduction, and provides a mechanism for redox-based physiological regulation.

Full Text

Duke Authors

Cited Authors

  • Hess, DT; Matsumoto, A; Kim, S-O; Marshall, HE; Stamler, JS

Published Date

  • February 2005

Published In

Volume / Issue

  • 6 / 2

Start / End Page

  • 150 - 166

PubMed ID

  • 15688001

Pubmed Central ID

  • 15688001

International Standard Serial Number (ISSN)

  • 1471-0072

Digital Object Identifier (DOI)

  • 10.1038/nrm1569

Language

  • eng

Conference Location

  • England