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Primary muscle lymphoma: clinical and imaging findings.

Publication ,  Journal Article
Lee, VS; Martinez, S; Coleman, RE
Published in: Radiology
April 1997

PURPOSE: To assess the clinical and imaging findings in primary muscle lymphoma. MATERIALS AND METHODS: Seven patients with biopsy-proved primary muscle lymphoma without evidence of systemic disease underwent imaging with plain radiography or computed tomography (CT) and magnetic resonance (MR) imaging. Four underwent bone scintigraphy, and two underwent gallium scintigraphy and fluorine-18 fluorodeoxyglucose (FDG) positron emission tomography (PET) before and after therapy. RESULTS: Plain radiographs at initial examination (n = 5) showed no bone abnormalities. Soft-tissue masses and bone marrow involvement showed isoattenuation at CT (n = 3), but at MR imaging (n = 7), all masses demonstrated increased signal intensity on T2-weighted images that involved multiple muscle compartments and typically spanned a long segment of the extremity. Adjacent bone disease was less extensive than muscle disease, and, in most cases, subcutaneous stranding or extension was observed adjacent to the masses. Good size correlation was observed between findings at MR imaging, gallium scintigraphy, and FDG PET. Two patients developed recurrent multifocal muscle lymphoma several years after initial examination. CONCLUSION: The presence of an extensive soft-tissue mass with infiltration of adjacent subcutaneous fat and minimal or no extension into the bone marrow cavity at MR imaging and normal plain radiographic findings may suggest primary muscle lymphoma.

Duke Scholars

Published In

Radiology

DOI

ISSN

0033-8419

Publication Date

April 1997

Volume

203

Issue

1

Start / End Page

237 / 244

Location

United States

Related Subject Headings

  • Tomography, X-Ray Computed
  • Tomography, Emission-Computed
  • Nuclear Medicine & Medical Imaging
  • Muscle Neoplasms
  • Middle Aged
  • Male
  • Magnetic Resonance Imaging
  • Lymphoma, Non-Hodgkin
  • Humans
  • Gallium Radioisotopes
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Lee, V. S., Martinez, S., & Coleman, R. E. (1997). Primary muscle lymphoma: clinical and imaging findings. Radiology, 203(1), 237–244. https://doi.org/10.1148/radiology.203.1.9122401
Lee, V. S., S. Martinez, and R. E. Coleman. “Primary muscle lymphoma: clinical and imaging findings.Radiology 203, no. 1 (April 1997): 237–44. https://doi.org/10.1148/radiology.203.1.9122401.
Lee VS, Martinez S, Coleman RE. Primary muscle lymphoma: clinical and imaging findings. Radiology. 1997 Apr;203(1):237–44.
Lee, V. S., et al. “Primary muscle lymphoma: clinical and imaging findings.Radiology, vol. 203, no. 1, Apr. 1997, pp. 237–44. Pubmed, doi:10.1148/radiology.203.1.9122401.
Lee VS, Martinez S, Coleman RE. Primary muscle lymphoma: clinical and imaging findings. Radiology. 1997 Apr;203(1):237–244.
Journal cover image

Published In

Radiology

DOI

ISSN

0033-8419

Publication Date

April 1997

Volume

203

Issue

1

Start / End Page

237 / 244

Location

United States

Related Subject Headings

  • Tomography, X-Ray Computed
  • Tomography, Emission-Computed
  • Nuclear Medicine & Medical Imaging
  • Muscle Neoplasms
  • Middle Aged
  • Male
  • Magnetic Resonance Imaging
  • Lymphoma, Non-Hodgkin
  • Humans
  • Gallium Radioisotopes