Familial benign intracranial hypertension and depression.

Journal Article (Journal Article)

Two sisters developed benign intracranial hypertension (BIH) two weeks following the resolution of a major depressive episode. The association of BIH and a major affective disorder in genetically related individuals has not been previously reported to our knowledge. Both conditions are associated with disturbances in the hypothalamic-pituitary-adrenal axis. Falling corticosteroid levels in a resolving depression may result in impaired cerebrospinal fluid absorption and subsequent BIH.

Full Text

Duke Authors

Cited Authors

  • Coffey, CE; Ross, DR; Massey, EW; Olanow, CW

Published Date

  • February 1, 1982

Published In

Volume / Issue

  • 9 / 1

Start / End Page

  • 45 - 47

PubMed ID

  • 7093825

International Standard Serial Number (ISSN)

  • 0317-1671

Digital Object Identifier (DOI)

  • 10.1017/s0317167100043626


  • eng

Conference Location

  • England