FlyRNAi: the Drosophila RNAi screening center database.

Journal Article (Journal Article)

RNA interference (RNAi) has become a powerful tool for genetic screening in Drosophila. At the Drosophila RNAi Screening Center (DRSC), we are using a library of over 21,000 double-stranded RNAs targeting known and predicted genes in Drosophila. This library is available for the use of visiting scientists wishing to perform full-genome RNAi screens. The data generated from these screens are collected in the DRSC database ( in a flexible format for the convenience of the scientist and for archiving data. The long-term goal of this database is to provide annotations for as many of the uncharacterized genes in Drosophila as possible. Data from published screens are available to the public through a highly configurable interface that allows detailed examination of the data and provides access to a number of other databases and bioinformatics tools.

Full Text

Duke Authors

Cited Authors

  • Flockhart, I; Booker, M; Kiger, A; Boutros, M; Armknecht, S; Ramadan, N; Richardson, K; Xu, A; Perrimon, N; Mathey-Prevot, B

Published Date

  • January 1, 2006

Published In

Volume / Issue

  • 34 / Database issue

Start / End Page

  • D489 - D494

PubMed ID

  • 16381918

Pubmed Central ID

  • PMC1347476

Electronic International Standard Serial Number (EISSN)

  • 1362-4962

Digital Object Identifier (DOI)

  • 10.1093/nar/gkj114


  • eng

Conference Location

  • England