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Effects of quitting smoking on EEG activation and attention last for more than 31 days and are more severe with stress, dependence, DRD2 A1 allele, and depressive traits.

Publication ,  Journal Article
Gilbert, D; McClernon, J; Rabinovich, N; Sugai, C; Plath, L; Asgaard, G; Zuo, Y; Huggenvik, J; Botros, N
Published in: Nicotine Tob Res
April 2004

Changes in physiology and attentional performance associated with smoking abstinence were characterized in 67 female smokers during low-stress and high-stress conditions. Abstinence was associated with decreases in cognitive performance, heart rate, and electroencephalographic (EEG) activation but with no change in serum estradiol or progesterone. Effects of quitting showed no tendency to resolve across the 31 days of abstinence. EEG deactivation and heart rate slowing were greater during a math task (high stress) than during relaxation (low stress). Individuals high in trait depression or nicotine dependence or with at least one dopamine D(2) receptor A1 allele experienced greater EEG deactivation following abstinence, especially in the right hemisphere during the stressful task. Thus, findings support the situation x trait adaptive response model of abstinence effects and emphasize the value of multiple dependent measures when characterizing abstinence responses.

Duke Scholars

Published In

Nicotine Tob Res

DOI

ISSN

1462-2203

Publication Date

April 2004

Volume

6

Issue

2

Start / End Page

249 / 267

Location

England

Related Subject Headings

  • Tobacco Use Disorder
  • Time Factors
  • Stress, Psychological
  • Smoking Cessation
  • Receptors, Dopamine D2
  • Public Health
  • Polymorphism, Genetic
  • Nicotine
  • Humans
  • Heart Rate
 

Citation

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Chicago
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Gilbert, D., McClernon, J., Rabinovich, N., Sugai, C., Plath, L., Asgaard, G., … Botros, N. (2004). Effects of quitting smoking on EEG activation and attention last for more than 31 days and are more severe with stress, dependence, DRD2 A1 allele, and depressive traits. Nicotine Tob Res, 6(2), 249–267. https://doi.org/10.1080/14622200410001676305
Gilbert, David, Joseph McClernon, Norka Rabinovich, Chihiro Sugai, Louisette Plath, Greg Asgaard, Yantao Zuo, Jodi Huggenvik, and Nazeih Botros. “Effects of quitting smoking on EEG activation and attention last for more than 31 days and are more severe with stress, dependence, DRD2 A1 allele, and depressive traits.Nicotine Tob Res 6, no. 2 (April 2004): 249–67. https://doi.org/10.1080/14622200410001676305.
Gilbert D, McClernon J, Rabinovich N, Sugai C, Plath L, Asgaard G, et al. Effects of quitting smoking on EEG activation and attention last for more than 31 days and are more severe with stress, dependence, DRD2 A1 allele, and depressive traits. Nicotine Tob Res. 2004 Apr;6(2):249–67.
Gilbert, David, et al. “Effects of quitting smoking on EEG activation and attention last for more than 31 days and are more severe with stress, dependence, DRD2 A1 allele, and depressive traits.Nicotine Tob Res, vol. 6, no. 2, Apr. 2004, pp. 249–67. Pubmed, doi:10.1080/14622200410001676305.
Gilbert D, McClernon J, Rabinovich N, Sugai C, Plath L, Asgaard G, Zuo Y, Huggenvik J, Botros N. Effects of quitting smoking on EEG activation and attention last for more than 31 days and are more severe with stress, dependence, DRD2 A1 allele, and depressive traits. Nicotine Tob Res. 2004 Apr;6(2):249–267.
Journal cover image

Published In

Nicotine Tob Res

DOI

ISSN

1462-2203

Publication Date

April 2004

Volume

6

Issue

2

Start / End Page

249 / 267

Location

England

Related Subject Headings

  • Tobacco Use Disorder
  • Time Factors
  • Stress, Psychological
  • Smoking Cessation
  • Receptors, Dopamine D2
  • Public Health
  • Polymorphism, Genetic
  • Nicotine
  • Humans
  • Heart Rate