Striatal dopamine D2/D3 receptor availability in male smokers.


Journal Article

It has been reported that the activation of the nicotine receptor evokes central endogenous dopamine release. However, whether smoking affects striatal dopamine D(2)/D(3) availability over the long run has not been well established in vivo. Fifteen male smokers and their matching controls were recruited. Striatal dopamine D(2)/D(3) receptor availability was assessed by single photon emission computed tomography with [(123)]IBZM Iodo-benzaimide. There was no significant difference in striatal D(2)/D(3) receptor availability between smokers and controls.

Full Text

Duke Authors

Cited Authors

  • Yang, YK; Yao, WJ; McEvoy, JP; Chu, CL; Lee, IH; Chen, PS; Yeh, TL; Chiu, NT

Published Date

  • January 30, 2006

Published In

Volume / Issue

  • 146 / 1

Start / End Page

  • 87 - 90

PubMed ID

  • 16343861

Pubmed Central ID

  • 16343861

International Standard Serial Number (ISSN)

  • 0165-1781

Digital Object Identifier (DOI)

  • 10.1016/j.pscychresns.2005.09.008


  • eng

Conference Location

  • Ireland