Striatal dopamine D2/D3 receptor availability in male smokers.

Journal Article (Journal Article)

It has been reported that the activation of the nicotine receptor evokes central endogenous dopamine release. However, whether smoking affects striatal dopamine D(2)/D(3) availability over the long run has not been well established in vivo. Fifteen male smokers and their matching controls were recruited. Striatal dopamine D(2)/D(3) receptor availability was assessed by single photon emission computed tomography with [(123)]IBZM Iodo-benzaimide. There was no significant difference in striatal D(2)/D(3) receptor availability between smokers and controls.

Full Text

Duke Authors

Cited Authors

  • Yang, YK; Yao, WJ; McEvoy, JP; Chu, CL; Lee, IH; Chen, PS; Yeh, TL; Chiu, NT

Published Date

  • January 30, 2006

Published In

Volume / Issue

  • 146 / 1

Start / End Page

  • 87 - 90

PubMed ID

  • 16343861

International Standard Serial Number (ISSN)

  • 0165-1781

Digital Object Identifier (DOI)

  • 10.1016/j.pscychresns.2005.09.008


  • eng

Conference Location

  • Ireland