Large postnatally acquired porencephalic cysts: unexpected developmental outcomes.

Journal Article (Journal Article)

To determine the neurodevelopmental outcome for infants with posthemorrhagic intraparenchymal cysts, we reviewed retrospectively clinical, ultrasonographic, and developmental features in 16 affected children. At a mean follow-up age of 33 months, five subjects had normal cognitive outcomes (developmental quotient [DQ] or IQ greater than 83), nine had borderline to mild deficits (DQ or IQ, 52 to 83), but only three had moderate to severe deficits (DQ or IQ less than 52). Spastic cerebral palsy was present in 13 (81%); only one child (6%) had a chronic seizure disorder requiring medication. Cognitively normal children were less likely to have had neonatal seizures (P less than .05) and tended to have more localized cysts. Otherwise, we found no relationship between outcome and neonatal clinical or laboratory findings. Overall, these results suggest that although motor deficits are common in infants with severe intraventricular hemorrhage and porencephalic cysts, cognitive outcomes may be more favorable than has been suspected previously.

Full Text

Duke Authors

Cited Authors

  • Blackman, JA; McGuinness, GA; Bale, JF; Smith, WL

Published Date

  • January 1, 1991

Published In

Volume / Issue

  • 6 / 1

Start / End Page

  • 58 - 64

PubMed ID

  • 2002203

International Standard Serial Number (ISSN)

  • 0883-0738

Digital Object Identifier (DOI)

  • 10.1177/088307389100600113


  • eng

Conference Location

  • United States