Localized intestinal perforation following intravenous indomethacin for patent ductus arteriosus.

Journal Article (Journal Article)

We describe a very low birth weight infant given intravenous indomethacin for a symptomatic patent ductus arteriosus who subsequently developed a gastrointestinal perforation. Although this is a well-known complication of enteral preparations, it has not been described with the intravenous form. Various mechanisms described in the literature by which the intravenous route of administration may compromise the bowel are presented. Although rare, gastrointestinal complications with intravenous indomethacin may become more prevalent with its increased use.

Full Text

Duke Authors

Cited Authors

  • Scholz, TD; McGuinness, GA

Published Date

  • September 1988

Published In

Volume / Issue

  • 7 / 5

Start / End Page

  • 773 - 775

PubMed ID

  • 3183883

International Standard Serial Number (ISSN)

  • 0277-2116

Digital Object Identifier (DOI)

  • 10.1097/00005176-198809000-00026


  • eng

Conference Location

  • United States